Description

2-Bromo-4-Fluoro-1,1'-Biphenyl is a high-purity halogenated biphenyl derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in providing a versatile halogenated aromatic scaffold for constructing complex molecules through cross-coupling and functional group transformations. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring a halogenated biphenyl core.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and other crop protection agents.
• Material Science Research: Serves as a precursor for the development of organic electronic materials, such as ligands for OLEDs and other functional polymers.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form more complex biaryl systems.
• Ligand and Catalyst Development: Utilized in the preparation of specialized ligands for metal-organic frameworks (MOFs) and homogeneous catalysis.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D labs exploring new synthetic pathways and novel compound libraries.

Basic Information

Product Name	2-Bromo-4-Fluoro-1,1'-Biphenyl
CAS No.	53591-98-3
Molecular Formula	C12H8BrF
Molecular Weight	251.10 g/mol
Synonyms	2-Bromo-4-fluorobiphenyl; 4-Fluoro-2-bromobiphenyl; 1-Bromo-2-(4-fluorophenyl)benzene; [1,1'-Biphenyl]-2-bromo-4-fluoro; 2-(4-Fluorophenyl)bromobenzene; Biphenyl, 2-bromo-4-fluoro-; 2-Bromo-4-fluoro-1,1'-biphenyl
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-Fluoro-1,1'-Biphenyl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment to guarantee batch-to-batch consistency and support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.