Description

(R)-(-)-Hexahydromandelic Acid CAS NO 53585-93-6 is a high-purity chiral building block and intermediate of significant importance in asymmetric synthesis. Its value lies in its utility for constructing complex, optically active molecules, particularly in the development of active pharmaceutical ingredients (APIs). This compound is essential for research and production teams in the pharmaceutical, agrochemical, and fine chemical industries who require enantiomerically pure intermediates for advanced synthesis.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of enantiomerically pure drugs, particularly for cardiovascular and central nervous system (CNS) agents.
• Asymmetric Synthesis: Used as a starting material or resolving agent in catalytic and stoichiometric asymmetric reactions to introduce chirality.
• Agrochemical Development: Employed in the research and production of chiral pesticides and herbicides where specific stereochemistry is required for bioactivity.
• Fine Chemical Production: Serves as a precursor for specialty chemicals, flavors, and fragrances that demand high optical purity.
• Academic & Industrial R&D: A valuable tool for chemists in process development and methodological studies in stereoselective chemistry.

Basic Information

Product Name	(R)-(-)-Hexahydromandelic Acid
CAS No.	53585-93-6
Molecular Formula	C8H16O3
Molecular Weight	160.21 g/mol
Synonyms	(R)-2-Cyclohexyl-2-hydroxyacetic acid; (R)-Cyclohexylglycolic acid; (R)-α-Hydroxycyclohexaneacetic acid; (R)-HHA; (R)-Hexahydromandelic acid; (2R)-2-Hydroxy-2-cyclohexylacetic acid; (R)-(-)-Cyclohexylhydroxyacetic acid
EINECS	Contact for details

Quality Control

Our (R)-(-)-Hexahydromandelic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets stringent specifications for pharmaceutical and research applications. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Enantiomeric Excess (Chiral HPLC)	≥99.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.