Description

(1Alpha,2Alpha,3Beta,6Beta)-1,2,3,6-Tetrahydromethyl-3,6-Methanophthalic Anhydride is a specialized bicyclic anhydride building block of significant interest in advanced organic synthesis. Its unique bridged structure and reactive anhydride group make it a valuable precursor for creating complex molecular architectures with tailored properties. This high-purity intermediate is primarily sought by research and development teams in the pharmaceutical and advanced materials sectors for synthesizing novel active pharmaceutical ingredients (APIs) and functional polymers.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex, bridged-ring drug candidates and novel active pharmaceutical ingredients (APIs).
• Advanced Polymer Synthesis: Used as a monomer or cross-linking agent for producing high-performance polyimides, epoxy resins, and other specialty polymers with enhanced thermal and mechanical properties.
• Agrochemical Research: Serves as a precursor in the development of new herbicides and pesticides with unique modes of action.
• Liquid Crystal & OLED Materials: Employed in the synthesis of rigid, anisotropic core structures for electronic display and lighting applications.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry and the exploration of new chemical spaces.
• Curing Agent for Epoxy Resins: Functions as a latent or high-temperature curing agent, contributing to improved heat resistance in composite materials.

Basic Information

Product Name	(1Alpha,2Alpha,3Beta,6Beta)-1,2,3,6-Tetrahydromethyl-3,6-Methanophthalic Anhydride
CAS No.	53584-57-9
Molecular Formula	C12H12O3
Molecular Weight	204.22 g/mol
Synonyms	1,2,3,6-Tetrahydro-1,2,3,6-tetramethyl-3,6-methanophthalic anhydride; 3,6-Methanophthalic anhydride, 1,2,3,6-tetrahydro-1,2,3,6-tetramethyl-; 1,2,3,6-Tetramethyl-3,6-methanophthalic anhydride; endo-1,2,3,6-Tetrahydro-1,2,3,6-tetramethyl-3,6-methanophthalic anhydride; Bicyclo[2.2.1]hept-5-ene-2,3-dicarboxylic anhydride, 1,2,3,6-tetrahydro-1,2,3,6-tetramethyl-; TMAnh; Tetramethyl nadic anhydride (TMNA)
EINECS	Contact for details

Quality Control

Our production of (1Alpha,2Alpha,3Beta,6Beta)-1,2,3,6-Tetrahydromethyl-3,6-Methanophthalic Anhydride adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is fully characterized using advanced analytical techniques including NMR, HPLC, and GC to confirm identity and assay. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can compromise product integrity. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Melting Point	102 - 108 °C
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.