Description

1-[2-Morpholinoethyl]-3-Phenylquinazoline-2,4(1H,3H)-Dione Monohydrochloride is a high-purity, synthetic organic compound primarily utilized as a key pharmaceutical intermediate. This compound matters for its role in the research and development of novel therapeutic agents, offering a critical building block for medicinal chemists. It is needed by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers focused on developing new chemical entities, particularly in areas requiring complex heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders or other therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop and optimize new pharmacologically active molecules.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and impurity profiling.
• Biochemical Research: May be utilized in biochemical assays to study enzyme interactions or receptor binding activities.
• Process Chemistry Development: Acts as a starting material or intermediate in scaling up synthetic routes for active pharmaceutical ingredients (APIs).

Basic Information

Product Name	1-[2-Morpholinoethyl]-3-Phenylquinazoline-2,4(1H,3H)-Dione Monohydrochloride
CAS No.	53412-85-4
Molecular Formula	C20H20N3O3·HCl
Molecular Weight	387.85 g/mol (free base: 350.39 g/mol)
Synonyms	3-Phenyl-1-(2-morpholinoethyl)quinazoline-2,4(1H,3H)-dione hydrochloride; 1-(2-Morpholin-4-ylethyl)-3-phenylquinazoline-2,4(1H,3H)-dione hydrochloride; 3-Phenyl-1-[2-(4-morpholinyl)ethyl]-2,4(1H,3H)-quinazolinedione monohydrochloride; Quinazoline-2,4(1H,3H)-dione, 1-[2-(4-morpholinyl)ethyl]-3-phenyl-, monohydrochloride; 53412-85-4 (CAS); 1-(2-Morpholinoethyl)-3-phenyl-2,4-dihydroquinazoline-2,4-dione hydrochloride
EINECS	Contact for details

Quality Control

Our 1-[2-Morpholinoethyl]-3-Phenylquinazoline-2,4(1H,3H)-Dione Monohydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets exacting standards for research and development use. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.