Description

6-Bromo-4-Chloro-2-Methylquinoline is a high-purity halogenated quinoline derivative, a crucial advanced intermediate in organic synthesis. Its value lies in providing a versatile, functionalized scaffold for constructing complex molecules in pharmaceutical and agrochemical research. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications such as drug discovery and the synthesis of active ingredients.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of potential drug candidates, particularly in the development of kinase inhibitors, antimicrobial agents, and other biologically active quinoline-based compounds.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides, leveraging the quinoline core's bioactivity.
• Material Science Research: Serves as a precursor for the development of organic electronic materials, ligands for catalysis, and functional dyes.
• Chemical Research & Development: Employed in academic and industrial labs for method development, cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig), and exploring novel synthetic pathways.
• Complex Molecule Construction: The bromo and chloro substituents offer distinct reactivity profiles for sequential functionalization, enabling the precise assembly of complex molecular architectures.

Basic Information

Product Name	6-Bromo-4-Chloro-2-Methylquinoline
CAS No.	53364-85-5
Molecular Formula	C₁₀H₇BrClN
Molecular Weight	256.53 g/mol
Synonyms	4-Chloro-6-bromo-2-methylquinoline; 2-Methyl-6-bromo-4-chloroquinoline; 6-Bromo-4-chloro-2-methylquinoline; Quinoline, 6-bromo-4-chloro-2-methyl-; 53364-85-5
EINECS	Contact for details

Quality Control

Our 6-Bromo-4-Chloro-2-Methylquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided and available upon request, supporting compliance with cGMP and ISO standards for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.