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4-o-Acetyl-α-n-Acetylneuraminyl-(2-3)-Lactose CAS NO 53248-77-4
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CAS No.:53248-77-4
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
4-o-Acetyl-α-n-Acetylneuraminyl-(2-3)-Lactose is a complex, acetylated sialyllactose derivative, a key intermediate in glycobiology research and synthesis. This compound is essential for studying and mimicking biological recognition processes involving sialic acid-containing glycoconjugates. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic sectors for the development of glycan-based therapeutics, vaccines, and analytical standards.
Application
- Glycobiology Research: A critical intermediate for studying sialic acid metabolism, cell signaling, and pathogen-host interactions.
- Pharmaceutical Development: Used in the synthesis of novel glycoconjugate vaccines and therapeutic agents targeting influenza, rotavirus, and other pathogens.
- Diagnostic Reagent Synthesis: Serves as a precursor for manufacturing high-specificity diagnostic tools and biosensors.
- Enzymatic Substrate: Acts as a specific substrate for sialidases (neuraminidases) and sialyltransferases in enzyme characterization assays.
- Reference Standard: Provides a certified standard for quality control and analytical method development in carbohydrate chemistry.
- Biomimetic Material Synthesis: Used to create synthetic glycopolymers and surfaces that mimic natural cell membranes for biomedical applications.
Basic Information
| Product Name | 4-o-Acetyl-α-n-Acetylneuraminyl-(2-3)-Lactose |
| CAS No. | 53248-77-4 |
| Molecular Formula | C31H51NO23 |
| Molecular Weight | 805.73 g/mol |
| Synonyms | 4-O-Acetyl-α-N-acetylneuraminyl-(2→3)-lactose; 4-O-Acetyl-α-Neu5Ac-(2-3)-Lac; 4-O-Acetyl-α-sialyllactose; Acetylated Sialyllactose; 4-O-Acetyl-N-acetylneuraminosyl-lactose; 4-AcO-α-Neu5Ac-(2→3)-β-D-Gal-(1→4)-D-Glc; Sialyl-lactose derivative (acetylated); Glycan intermediate 53248-77-4 |
| EINECS | Contact for details |
Quality Control
Every batch of 4-o-Acetyl-α-n-Acetylneuraminyl-(2-3)-Lactose is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality system is designed to meet the stringent requirements of research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity (by HPLC), identity confirmation (NMR, MS), and impurity profiles is provided with each shipment.
Storage
Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation or storage under an inert atmosphere. Allow the sealed container to reach room temperature before opening to prevent condensation.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder |
| Identification (HPLC) | Conforms to reference standard |
| Identification (NMR) | Conforms to structure |
| Purity (HPLC) | ≥ 95.0% |
| Water Content (KF) | ≤ 5.0% |
| Specific Rotation | Contact for details |
| Heavy Metals | < 20 ppm |
| Bacterial Endotoxins | < 1.0 EU/mg (if applicable) |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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