Description

(1S,2S)-N,N,N'',N''-Tetramethyl-1,2-cyclohexanediamine is a high-purity, chiral diamine ligand and organocatalyst. This compound is valued for its ability to induce stereoselectivity in a wide range of asymmetric synthetic transformations, offering researchers and manufacturers a powerful tool for creating enantiomerically enriched molecules. It is a critical component for pharmaceutical intermediates, advanced material synthesis, and specialty chemical production where precise chiral control is required.

Application

• Asymmetric Catalysis: Serves as a privileged chiral ligand in metal-catalyzed reactions, including additions and cross-couplings.
• Organocatalysis: Acts as a catalyst or catalyst precursor in enantioselective organic reactions such as aldol condensations and Michael additions.
• Pharmaceutical Synthesis: Used in the production of active pharmaceutical ingredients (APIs) and key chiral intermediates for drug discovery and development.
• Agrochemicals: Employed in the synthesis of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Fine Chemical Manufacturing: Facilitates the production of specialty flavors, fragrances, and other high-value chiral compounds.
• Polymer Science: Utilized as a monomer or chain modifier in the synthesis of polymers with specific stereochemical properties.
• Academic & Industrial Research: A valuable reagent for methodological development in synthetic organic chemistry laboratories.

Basic Information

Product Name	(1S,2S)-N,N,N'',N''-Tetramethyl-1,2-cyclohexanediamine
CAS No.	53152-68-4
Molecular Formula	C10H22N2
Molecular Weight	170.30 g/mol
Synonyms	(1S,2S)-1,2-Bis(dimethylamino)cyclohexane; (1S,2S)-TMCDA; (1S,2S)-Tetramethylcyclohexanediamine; (1S,2S)-N,N,N',N'-Tetramethyl-1,2-diaminocyclohexane; (1S,2S)-Cyclohexane-1,2-diamine, N,N,N',N'-tetramethyl-; (1S,2S)-1,2-Diamino-1,2-bis(dimethylamino)cyclohexane; (S,S)-TMCDA; (S,S)-Tetramethyl-1,2-cyclohexanediamine
EINECS	Contact for details

Quality Control

Our (1S,2S)-N,N,N'',N''-Tetramethyl-1,2-cyclohexanediamine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high chemical and enantiomeric purity, meeting the stringent requirements for research and industrial applications. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and chiral excess are provided to guarantee consistent performance and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.