Description

(5-Amino-2,2-Dimethyl-[1,3]Dioxan-5-Yl)-Methanol is a versatile amino-protected diol building block, also known as a serine acetonide derivative, with the CAS number 53104-32-8. This compound is valued for its role as a key chiral intermediate in the synthesis of complex pharmaceuticals and fine chemicals, offering a protected amine and alcohol functionality for selective reactions. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and neurological drug candidates.
• Peptide Synthesis: Used in the preparation of modified amino acids and peptide mimetics where side-chain protection is required.
• Agrochemical Synthesis: Serves as a precursor in the development of advanced herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Employed in the creation of chiral ligands for asymmetric catalysis and organocatalysts.
• Polymer Chemistry: Acts as a monomer or chain extender for synthesizing specialty polyesters, polyurethanes, and polyamides with specific functional groups.
• Chemical Research: A valuable reagent for academic and industrial research in organic synthesis and medicinal chemistry.

Basic Information

Product Name	(5-Amino-2,2-Dimethyl-[1,3]Dioxan-5-Yl)-Methanol
CAS No.	53104-32-8
Molecular Formula	C7H15NO3
Molecular Weight	161.20 g/mol
Synonyms	5-Amino-2,2-dimethyl-1,3-dioxane-5-methanol; Serine Acetonide; (5-Amino-2,2-dimethyl-1,3-dioxan-5-yl)methanol; 2,2-Dimethyl-5-(hydroxymethyl)-1,3-dioxan-5-amine; 5-(Hydroxymethyl)-2,2-dimethyl-1,3-dioxan-5-amine; Amino-protected Serinol; D,L-Serine Acetonide
EINECS	Contact for details

Quality Control

Our (5-Amino-2,2-Dimethyl-[1,3]Dioxan-5-Yl)-Methanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) with detailed specifications from HPLC, NMR, and chiral analysis are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (enantiomeric excess)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.