Description

(3R,4R,5R)-3,4-Dihydroxy-5-(Hydroxymethyl)-3-Methyldihydrofuran-2(3H)-One is a high-purity, stereochemically defined carbohydrate derivative and a key chiral building block in organic synthesis. Its precise stereochemistry and functional group array make it an invaluable intermediate for the development of complex molecules, particularly in the pharmaceutical sector. This compound is essential for researchers and manufacturers in fine chemical, pharmaceutical, and agrochemical industries seeking to synthesize nucleoside analogs, antiviral agents, and other bioactive compounds with high enantiomeric purity.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of nucleoside and nucleotide analogs with potential antiviral or anticancer activity.
• Fine Chemical Synthesis: Used as a building block for complex carbohydrates, natural products, and other stereochemically demanding organic molecules.
• Agrochemical Research: Serves as a precursor in the development of novel, chiral active ingredients with specific biological functions.
• Biochemical Research: Employed in enzymatic studies and as a substrate or inhibitor for glycosidases and other carbohydrate-processing enzymes.
• Academic & R&D: A valuable reagent for methodological development in asymmetric synthesis and medicinal chemistry research programs.

Basic Information

Product Name	(3R,4R,5R)-3,4-Dihydroxy-5-(Hydroxymethyl)-3-Methyldihydrofuran-2(3H)-One
CAS No.	53008-90-5
Molecular Formula	C6H10O5
Molecular Weight	162.14 g/mol
Synonyms	3-C-Methyl-D-ribono-1,4-lactone; (3R,4R,5R)-3,4-Dihydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-one; 3-C-Methyl-D-ribonolactone; 3-C-Methylribono-1,4-lactone; D-3-C-Methylribono-1,4-lactone; 3-Methyl-D-ribonolactone; 3-C-Methyl-D-ribono-y-lactone
EINECS	Contact for details

Quality Control

Our (3R,4R,5R)-3,4-Dihydroxy-5-(Hydroxymethyl)-3-Methyldihydrofuran-2(3H)-One is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee reproducible quality and supply chain transparency for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent decomposition. Recommended long-term storage at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.