Description

Technetium Tc 99M Diphosphonate is a diagnostic radiopharmaceutical agent used in nuclear medicine imaging. Its core value lies in its ability to target and visualize skeletal structures, providing critical diagnostic information for bone-related pathologies. This compound is essential for hospitals, diagnostic imaging centers, and radiopharmacies specializing in bone scintigraphy. The product is supplied as a sterile, non-pyrogenic kit for the preparation of Technetium Tc 99m Medronate Injection.

Application

• Bone Scintigraphy (Bone Scan): Primary diagnostic tool for detecting bone metastases, osteomyelitis, fractures, and other skeletal abnormalities.
• Evaluation of Prosthetic Joints: Used to assess loosening or infection in artificial joints such as hips and knees.
• Paget's Disease Assessment: Aids in diagnosing and monitoring the extent of Paget's disease of bone.
• Detection of Osteosarcoma: Helps in the localization and staging of primary bone cancers.
• Assessment of Bone Trauma: Useful for identifying stress fractures and other sports-related injuries not visible on standard X-rays.
• Renal Imaging (Secondary): While primarily skeletal, it can provide adjunctive information on renal morphology and function.

Basic Information

Product Name	Technetium Tc 99M Diphosphonate
CAS No.	52997-55-4
Molecular Formula	C2H6Na2O6P2 • xTc-99m
Molecular Weight	Contact for details
Synonyms	Technetium Tc 99m Medronate; Tc-99m MDP; Technetium (99mTc) Medronate; Sodium Medronate Tc-99m; MDP Kit; Bone Scan Agent; Technetium-99m Methylenediphosphonate; (99mTc)MDP
EINECS	Contact for details

Quality Control

Our Technetium Tc 99M Diphosphonate kits are manufactured under strict aseptic conditions in compliance with current Good Manufacturing Practices (cGMP). Each batch undergoes rigorous quality testing to ensure compliance with pharmacopeial standards (e.g., USP monographs for Radiopharmaceuticals). Certificates of Analysis (COA) are provided, detailing critical parameters such as radiochemical purity, pH, sterility, and apyrogenicity.

Storage

Preserve in the original, unopened kit vial within the provided lead shield. Store at controlled room temperature, 15-25°C (59-77°F). The kit components are strictly light-sensitive and must be protected from all light exposure. The final prepared injection is for single use only and must be administered promptly.

Specification

Item	Specification
Appearance	Sterile, non-pyrogenic lyophilized powder or solid cake
pH (after reconstitution)	5.0 - 7.0
Radiochemical Purity (HPLC/TLC)	≥ 90%
Sterility Test	Sterile
Bacterial Endotoxins (LAL)	< 175 EU/Vial
Tin Content (Assay)	Within labeled amount
Identification (γ-ray spectrometry)	Characteristic for Tc-99m

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.