Description

3-Methylene-1-Oxaspiro[4.5]Decan-2-One is a specialized spirocyclic lactone compound that serves as a valuable synthetic intermediate and building block in advanced organic synthesis. Its unique bridged bicyclic structure containing both a lactone and an exocyclic methylene group makes it a versatile precursor for constructing complex molecular architectures. This compound is primarily utilized by research and development chemists in the pharmaceutical, agrochemical, and fragrance industries for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those requiring spirocyclic or complex lactone frameworks.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, leveraging its reactive methylene group for further functionalization.
• Fragrance & Flavor Chemistry: Serves as a precursor for musk-like odorants and other specialty aroma chemicals due to its spirocyclic structure.
• Material Science Research: Investigated as a monomer or cross-linking agent for developing polymers with unique thermal or mechanical properties.
• Organic Synthesis Reagent: Employed in academic and industrial R&D for methodologies like cycloadditions, ring-opening reactions, and as a dienophile or Michael acceptor.
• Chemical Reference Standard: Supplied to analytical laboratories for method development, calibration, and quality control testing.

Basic Information

Product Name	3-Methylene-1-Oxaspiro[4.5]Decan-2-One
CAS No.	52978-85-5
Molecular Formula	C10H14O2
Molecular Weight	166.22 g/mol
Synonyms	3-Methylene-1-oxaspiro[4.5]decan-2-one; 1-Oxaspiro[4.5]dec-3-en-2-one, 3-methylene-; 3-Methylene-1-oxaspiro[4.5]decan-2-one; Spiro[4.5]decan-2-one, 3-methylene-1-oxa-; 3-Methylen-1-oxaspiro[4.5]decan-2-on; 3-Methylenoxaspiro[4.5]decan-2-on
EINECS	Contact for details

Quality Control

Our 3-Methylene-1-Oxaspiro[4.5]Decan-2-One is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chromatography (HPLC, GC) and spectroscopy (NMR, IR), to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality parameters. Our commitment to cGMP principles and stringent in-process controls guarantees a reliable supply of high-purity material for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider holding under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.