Description

n-Phthaloyl-Dl-Methionine is a protected derivative of the essential amino acid methionine, where the amino group is blocked by a phthaloyl group. This chemical modification is crucial for its primary role as a key chiral intermediate and protecting group reagent in sophisticated organic synthesis, particularly in peptide chemistry and pharmaceutical manufacturing. It is an essential material for research chemists and production facilities developing novel therapeutic agents, fine chemicals, and advanced materials where precise stereochemistry and functional group manipulation are required.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of chiral drugs, peptides, and complex bioactive molecules.
• Peptide Synthesis: Used as a protecting group for methionine during solid-phase and solution-phase peptide synthesis to prevent unwanted side reactions.
• Asymmetric Synthesis: Serves as a chiral auxiliary or starting material for the preparation of enantiomerically pure compounds.
• Biochemical Research: Employed in studies of amino acid metabolism, enzyme mechanisms, and protein engineering.
• Fine Chemical Production: Utilized in the manufacture of specialty chemicals, catalysts, and ligands for industrial processes.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	n-Phthaloyl-Dl-Methionine
CAS No.	52881-96-6
Molecular Formula	C₁₄H₁₅NO₄S
Molecular Weight	293.34 g/mol
Synonyms	N-Phthaloyl-DL-methionine; DL-Methionine, N-phthaloyl-; Phthalimidomethionine; 2-[(1,3-Dioxoisoindolin-2-yl)methylthio]butanoic acid; N-(1,3-Dioxoisoindolin-2-yl)-DL-methionine; Phthaloyl methionine; N-Phthaloylmethionine; N-Phthalimido-DL-methionine
EINECS	Contact for details

Quality Control

Our n-Phthaloyl-Dl-Methionine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and synthesis applications. Each lot is subjected to comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation by spectroscopic methods. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.