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(1R)-1,2,3,4,4Aβ,7,8,8Aα-Octahydro-4β-Isopropyl-1,6-Dimethyl-1α-Methoxynaphthalene CAS NO 52760-32-4


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CAS No.:52760-32-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(1R)-1,2,3,4,4Aβ,7,8,8Aα-Octahydro-4β-Isopropyl-1,6-Dimethyl-1α-Methoxynaphthalene is a high-purity, stereochemically defined decalin derivative with a methoxy functional group, serving as a critical chiral intermediate in advanced organic synthesis. Its rigid, polycyclic framework and specific stereochemistry make it invaluable for constructing complex molecular architectures with precise three-dimensional control. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to synthesize novel active ingredients and fine chemicals.

Application

  • Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel drug candidates, particularly in steroid and terpenoid-related therapeutic areas.
  • Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, leveraging its complex ring system for bioactivity.
  • Fragrance & Flavor Chemistry: Serves as a precursor for high-value aroma chemicals and flavorants due to its structural similarity to natural terpenes.
  • Material Science Research: Investigated as a monomer or additive for creating specialized polymers with unique thermal or mechanical properties.
  • Catalyst & Ligand Development: Employed as a scaffold for developing novel chiral ligands and organocatalysts used in asymmetric synthesis.
  • Academic & Industrial R&D: A valuable reference standard and starting material for methodological studies in synthetic organic chemistry.

Basic Information

Item Details
Product Name (1R)-1,2,3,4,4Aβ,7,8,8Aα-Octahydro-4β-Isopropyl-1,6-Dimethyl-1α-Methoxynaphthalene
CAS No. 52760-32-4
Molecular Formula C₁₆H₂₈O
Molecular Weight 236.39 g/mol
Synonyms (1R,4S,4aS,8aR)-4-Isopropyl-1,6-dimethyl-1-methoxy-1,2,3,4,4a,5,6,7,8,8a-decahydronaphthalene; (1R)-1-Methoxy-4-isopropyl-1,6-dimethyl-1,2,3,4,4a,7,8,8a-octahydronaphthalene; 1α-Methoxy-4β-isopropyl-1,6-dimethyldecalin; Decalin, 1-methoxy-4-(1-methylethyl)-1,6-dimethyl-, (1R,4S,4aS,8aR)-; Chiral Decalin Methoxy Derivative
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Quality Control

Our (1R)-1,2,3,4,4Aβ,7,8,8Aα-Octahydro-4β-Isopropyl-1,6-Dimethyl-1α-Methoxynaphthalene is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity verification by HPLC and GC, to ensure consistent identity, purity, and stereochemical integrity. Comprehensive Certificates of Analysis (COA) detailing all specifications are provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item Specification
Appearance Colorless to pale yellow clear liquid
Identification (IR) Conforms to structure
Purity (GC) ≥ 97.0%
Chiral Purity (Chiral HPLC) ≥ 98.0% ee
Water Content (KF) ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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