Description

α-Hydroxybenzylphosphinic Acid is an organophosphorus compound featuring a benzyl group substituted with both hydroxyl and phosphinic acid functionalities. This unique structure makes it a valuable intermediate and ligand in advanced chemical synthesis and material science. It is primarily sought by industries involved in the development of pharmaceuticals, agrochemicals, and specialty polymers where precise molecular architecture is critical.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting neurological or metabolic pathways.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, plant growth regulators, and fungicides due to its phosphorus-containing backbone.
• Ligand for Catalysis: Acts as a chelating ligand in transition metal catalysis for various organic transformations, including cross-coupling and asymmetric hydrogenation reactions.
• Flame Retardant Precursor: A potential intermediate in the manufacture of phosphorus-based flame retardants for polymers and textiles.
• Coordination Chemistry Research: Employed in academic and industrial R&D to study metal complexation and develop new materials with specific optical or magnetic properties.
• Specialty Polymer Modifier: Incorporated into polymer chains to impart specific characteristics such as improved adhesion, thermal stability, or biocompatibility.

Basic Information

Product Name	α-Hydroxybenzylphosphinic Acid
CAS No.	52705-43-8
Molecular Formula	C7H9O3P
Molecular Weight	172.12 g/mol
Synonyms	(Hydroxy(phenyl)methyl)phosphinic acid; α-Hydroxybenzylphosphinic Acid; Benzylphosphinic acid, α-hydroxy-; Hydroxy(phenyl)methylphosphinic acid; Phenyl(hydroxy)methylphosphinic acid; HPA (abbreviation); (α-Hydroxybenzyl)phosphonic acid (common misnomer); (1-Hydroxy-1-phenylethyl)phosphinic acid (related isomer)
EINECS	Contact for details

Quality Control

Our α-Hydroxybenzylphosphinic Acid is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and spectroscopic identification (NMR, IR), to ensure it meets precise customer specifications. Certificates of Analysis (COA) detailing all test results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed when not in use to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.