Description

2,2',3,3',4,5'-Hexachlorobiphenyl CAS NO 52663-66-8 is a specific congener of polychlorinated biphenyls (PCBs), a class of synthetic organic chemicals. This compound is of significant interest for analytical reference standards and environmental research due to its persistence and historical use. It is primarily required by analytical laboratories, environmental testing facilities, and research institutions for calibration, method development, and toxicological studies.

Application

• Analytical Reference Standard: Used as a certified reference material (CRM) for the calibration of instruments like GC-MS and HPLC in environmental analysis.
• Environmental Monitoring: Essential for the accurate quantification and identification of PCB congeners in soil, water, sediment, and air samples to assess contamination levels.
• Toxicological Research: Serves as a key compound in studies investigating the biochemical pathways, persistence, and health effects of specific PCB congeners.
• Method Development and Validation: Used by laboratories to develop, optimize, and validate analytical methods for PCB detection and congener-specific analysis.
• Quality Control/Quality Assurance (QC/QA): Employed as a spike or control sample to ensure the accuracy and precision of analytical data in compliance with regulatory methods.
• Regulatory Compliance Testing: Supports testing mandated by agencies such as the EPA, which requires congener-specific PCB analysis for environmental permits and site remediation.

Basic Information

Product Name	2,2',3,3',4,5'-Hexachlorobiphenyl
CAS No.	52663-66-8
Molecular Formula	C₁₂H₄Cl₆
Molecular Weight	360.88 g/mol
Synonyms	PCB 138; 2,2',3,3',4,5'-Hexachloro-1,1'-biphenyl; 2,2',3,3',4,5'-HexaCB; 2,2',3,3',4,5'-Hexachlorodiphenyl; Biphenyl, 2,2',3,3',4,5'-hexachloro-; 1,1'-Biphenyl, 2,2',3,3',4,5'-hexachloro-; IUPAC: 1,2,3,4-Tetrachloro-5-(2,3,4-trichlorophenyl)benzene (alternative numbering).
EINECS	Contact for details

Quality Control

Our high-purity 2,2',3,3',4,5'-Hexachlorobiphenyl is produced and handled under strict quality protocols to ensure identity, purity, and stability for critical analytical applications. Each batch is characterized using advanced techniques including gas chromatography (GC) and mass spectrometry (MS). A comprehensive Certificate of Analysis (COA) is provided, detailing purity, congener-specific identity confirmation, and chromatographic data to support your research and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). For long-term stability, storage at 2-8°C is recommended. Keep the container securely sealed in a well-ventilated area.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (GC-MS)	Conforms to reference standard
Purity (GC-FID/GC-MS)	≥ 98.0% (Area %)
Related Congeners (GC-MS)	≤ 1.0% (Total)
Solubility	Soluble in common organic solvents (e.g., hexane, toluene, acetone)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.