Description

Gm1-Pentasaccharide CAS NO 52659-37-7 is a high-purity, well-defined oligosaccharide derivative of the GM1 ganglioside, a critical component in neurobiology and immunology research. This compound serves as a vital reference standard and synthetic intermediate for the development of glycoconjugates and molecular probes. It is essential for researchers and manufacturers in the pharmaceutical, diagnostic, and life science sectors who require precise tools for studying carbohydrate-protein interactions, vaccine development, and neurological disorders.

Application

• Biochemical Research: Used as a reference standard and substrate in studies of ganglioside metabolism, glycosidase enzymes, and carbohydrate-binding proteins (lectins).
• Pharmaceutical Development: Serves as a key intermediate in the synthesis of glycoconjugate vaccines, targeted therapeutics, and diagnostic agents.
• Diagnostic Reagents: Employed in the development of immunoassays and biosensors for the detection of antibodies or pathogens that recognize GM1 epitopes.
• Neuroscience Studies: Applied in research related to neural development, cell signaling, and the pathology of diseases like Guillain-Barré syndrome.
• Glycobiology Tool: A critical reagent for probing glycan structure-function relationships and for the chemoenzymatic synthesis of complex carbohydrates.

Basic Information

Item	Detail
Product Name	Gm1-Pentasaccharide
CAS No.	52659-37-7
Molecular Formula	C56H95N3O31
Molecular Weight	1306.35 g/mol
Synonyms	GM1 Oligosaccharide; Ganglioside GM1 Pentasaccharide; β-D-Gal-(1→3)-β-D-GalNAc-(1→4)-[α-D-Neu5Ac-(2→3)]-β-D-Gal-(1→4)-β-D-Glc; Asialo-GM1 Pentasaccharide; II3Neu5Ac-GgOse4Cer; GM1-OS; Neu5Acα2-3Galβ1-3GalNAcβ1-4Galβ1-4Glc
EINECS	Contact for details

Quality Control

Our Gm1-Pentasaccharide is produced under stringent conditions to ensure batch-to-batch consistency and high purity, suitable for sensitive research applications. Quality is verified through a comprehensive suite of analytical techniques including HPLC, NMR, and Mass Spectrometry. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting purity, identity, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a desiccated environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a dry atmosphere before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0 %
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.