Description

6-Bromo-2,3-Dihydro-1H-Indene-1-Carboxylic Acid is a high-value, synthetically versatile brominated indane derivative that serves as a critical building block in advanced organic synthesis. Its unique fused-ring structure with both a carboxylic acid and a bromine substituent makes it an indispensable intermediate for constructing complex molecular architectures. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators, leveraging its halogenated indane core.
• Ligand and Catalyst Synthesis: Serves as a starting material for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Precursor: Employed in the research and development of organic electronic materials, such as semiconductors and light-emitting diodes (OLEDs).
• Chemical Biology Probe Development: Utilized to create tagged molecules for studying biological pathways and protein interactions.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specific brominated intermediates.

Basic Information

Product Name	6-Bromo-2,3-dihydro-1H-indene-1-carboxylic acid
CAS No.	52651-16-8
Molecular Formula	C10H9BrO2
Molecular Weight	241.08 g/mol
Synonyms	6-Bromo-1-indanecarboxylic acid; 1H-Indene-1-carboxylic acid, 6-bromo-2,3-dihydro-; 6-Bromoindane-1-carboxylic acid; 6-Bromo-2,3-dihydro-1H-indene-1-carboxylic acid; (6-Bromo-2,3-dihydro-1H-inden-1-yl)carboxylic acid; 6-Bromo-1-carboxyindane; 52651-16-8
EINECS	Contact for details

Quality Control

Our 6-Bromo-2,3-Dihydro-1H-Indene-1-Carboxylic Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, essential for sensitive synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of pharmaceutical and R&D customers, with specifications that can be aligned with cGMP standards for advanced intermediates upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.