Description

3-(2-Amino-Ethyl)-5-Methoxy-1H-Indole-2-Carboxylic Acid CAS NO 52648-13-2 is a high-purity indole derivative, a crucial building block in advanced organic synthesis. This compound is valued for its bifunctional structure, featuring both a carboxylic acid and an aminoethyl group, which makes it a versatile intermediate for constructing complex molecules. It is primarily sought after by pharmaceutical and biotechnology R&D teams for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those targeting neurological and psychiatric conditions.
• Biochemical Research: Used as a standard or reagent in proteomics and enzyme inhibition studies due to its indole core structure.
• Peptide Mimetics: Serves as a constrained amino acid analog for designing and synthesizing novel peptide-based therapeutics.
• Agrochemical Development: Employed in research for creating new plant growth regulators or selective herbicides.
• Material Science: Investigated as a monomer or functional additive for specialty polymers with unique optical or electronic properties.
• Fluorescent Probe Synthesis: Utilized in the development of indole-based fluorescent markers for cellular imaging and diagnostics.

Basic Information

Item	Details
Product Name	3-(2-Amino-Ethyl)-5-Methoxy-1H-Indole-2-Carboxylic Acid
CAS No.	52648-13-2
Molecular Formula	C₁₂H₁₄N₂O₃
Molecular Weight	234.25 g/mol
Synonyms	5-Methoxy-3-(2-aminoethyl)indole-2-carboxylic acid; 2-Carboxy-5-methoxy-3-(2-aminoethyl)indole; 3-(2-Aminoethyl)-5-methoxy-1H-indole-2-carboxylic acid; 5-Methoxy-3-(2-aminoethyl)-1H-indole-2-carboxylic acid; 52648-13-2; 3-(2-Aminoethyl)-5-methoxyindole-2-carboxylic acid; 5-Methoxy-3-(2-aminoethyl)indole-2-carboxylic acid; 3-(2-Aminoethyl)-5-methoxy-1H-indole-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of 3-(2-Amino-Ethyl)-5-Methoxy-1H-Indole-2-Carboxylic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support cGMP and ISO compliant manufacturing practices, and specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.