Description

Spiro[Bicyclo[2.2.1]Heptane-2,5(4H)-Oxazole], 4-Ethoxy-, [1-α-,2-Ba-(R*),4-α-]- (9Ci) is a high-purity, stereochemically defined spirocyclic compound that serves as a sophisticated chemical building block and chiral intermediate. Its unique fused bicyclic and oxazole structure makes it a valuable scaffold for advanced research and development, particularly in the synthesis of complex molecules. This compound is primarily sought by pharmaceutical R&D and fine chemical synthesis teams for developing novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-infective targets.
• Asymmetric Synthesis: Utilized as a chiral auxiliary or ligand precursor in catalytic asymmetric reactions to induce stereoselectivity.
• Advanced Material Research: Serves as a building block for developing specialty polymers, liquid crystals, or organic electronic materials with specific stereochemical properties.
• Agrochemical Development: Used in research for creating new, stereospecific active ingredients for crop protection.
• Academic & Institutional Research: Employed in synthetic organic chemistry studies focused on spirocyclic systems and heterocyclic compound reactivity.
• Process Chemistry & Scale-up: Serves as a critical intermediate for process development and optimization in kilo-lab and pilot plant settings.

Basic Information

Product Name	Spiro[Bicyclo[2.2.1]Heptane-2,5(4H)-Oxazole], 4-Ethoxy-, [1-α-,2-Ba-(R*),4-α-]- (9Ci)
CAS No.	52612-66-5
Molecular Formula	C11H17NO2
Molecular Weight	195.26 g/mol
Synonyms	4-Ethoxyspiro[bicyclo[2.2.1]heptane-2,5'-oxazolidine]; 4-Ethoxy-1-azaspiro[bicyclo[2.2.1]heptane-2,5'-oxazolidine]; [1α,2β(R*),4α]-4-Ethoxyspiro[bicyclo[2.2.1]heptane-2,5'-oxazolidine]; Spiro[bicyclo[2.2.1]heptane-2,5'(4H)-oxazole], 4-ethoxy-, [1α,2β(R*),4α]- (9CI); 52612-66-5; 4-Ethoxy-1-azaspiro[bicyclo[2.2.1]heptane-2,5'-oxazole]
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Each batch is characterized and tested using advanced analytical techniques including HPLC, GC, NMR, and chiral analysis to ensure identity, purity, and stereochemical integrity. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.