Description

(3As,4R,11As)-3A,7,8,10,11,11A-Hexahydro-4-Hydroxy-6-Methyl-3,10-Bis(Methylene)Cyclodeca[B]Furan-2,9(3H,4H)-Dione is a complex sesquiterpene lactone derivative with a fused furanone structure, offering a unique chemical scaffold for advanced synthesis. This compound matters as a versatile high-purity intermediate for pharmaceutical research and fine chemical manufacturing, where precise molecular architecture is critical. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for developing new active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block for the synthesis of potential drug candidates, particularly in oncology and anti-inflammatory research.
• Natural Product Synthesis: Used in the total or semi-synthesis of complex natural products and their analogs for biological evaluation.
• Agrochemical Research: Acts as a precursor for developing new plant growth regulators or bioactive agents with specific modes of action.
• Chemical Biology Probe: Utilized as a molecular scaffold to create probes for studying enzyme mechanisms or protein interactions.
• Material Science Research: Investigated as a monomer or precursor for specialized polymers with unique thermal or optical properties.
• Reference Standard: Supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	(3As,4R,11As)-3A,7,8,10,11,11A-Hexahydro-4-Hydroxy-6-Methyl-3,10-Bis(Methylene)Cyclodeca[B]Furan-2,9(3H,4H)-Dione
CAS No.	52591-19-2
Molecular Formula	C15H16O4
Molecular Weight	260.29 g/mol
Synonyms	6-Methyl-3,10-bis(methylene)cyclodeca[b]furan-2,9-dione, 3a,4,7,8,10,11,11a-hexahydro-4-hydroxy-, (3aR,4R,11aS)-; Alantolactone Isomer; Isoalantolactone (related but distinct isomer); Helenin derivative; Sesquiterpene lactone, 6-methyl-3,10-bis(methylene)-; (3aR,4R,11aS)-4-Hydroxy-6-methyl-3,10-bis(methylene)cyclodeca[b]furan-2,9-dione; 52591-19-2; Eupatolide analog.
EINECS	Contact for details

Quality Control

Our (3As,4R,11As)-3A,7,8,10,11,11A-Hexahydro-4-Hydroxy-6-Methyl-3,10-Bis(Methylene)Cyclodeca[B]Furan-2,9(3H,4H)-Dione is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client requirements for research or cGMP applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.