Description

2-Chloro-10-Piperazino-10,11-Dihydrodibenzo[B,F]Thiepin is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is of significant value in the research and development of novel therapeutic agents, particularly within the central nervous system (CNS) domain. It is primarily sought by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in medicinal chemistry and process development.

Application

• Key Intermediate in Pharmaceutical Synthesis: Serves as a critical building block for the development of novel psychotropic and neuroactive drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize biological activity and pharmacokinetic properties of lead compounds.
• Process Chemistry & Scale-Up: Employed in the development and optimization of scalable synthetic routes for active pharmaceutical ingredients (APIs).
• Reference Standard: Acts as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.
• Academic & Institutional Research: Utilized in universities and research institutes for exploratory studies in organic synthesis and pharmacology.

Basic Information

Product Name	2-Chloro-10-Piperazino-10,11-Dihydrodibenzo[B,F]Thiepin
CAS No.	52548-24-0
Molecular Formula	C20H22ClN2S
Molecular Weight	357.92 g/mol
Synonyms	2-Chloro-10-(1-piperazinyl)-10,11-dihydrodibenzo[b,f]thiepin; 10,11-Dihydro-2-chloro-10-(1-piperazinyl)dibenzo[b,f]thiepin; 52548-24-0; Dibenzo[b,f]thiepin, 10,11-dihydro-2-chloro-10-(1-piperazinyl)-; Zotepine Impurity; Zotepine Related Compound
EINECS	Contact for details

Quality Control

Our 2-Chloro-10-Piperazino-10,11-Dihydrodibenzo[B,F]Thiepin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and a Certificate of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles suitable for pharmaceutical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.