Description

2-Iodo-5-Methylbenzoic Acid is a versatile iodinated aromatic carboxylic acid building block of significant importance in advanced organic synthesis. Its core value proposition lies in enabling the precise introduction of iodine and a carboxylic acid functional group into complex molecular architectures, facilitating further cross-coupling reactions and derivatizations. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it serves as a key intermediate in the development of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring halogenated aromatic motifs.
• Agrochemical Synthesis: Used in the research and production of herbicides, fungicides, and other crop protection agents.
• Material Science Research: Serves as a monomer or precursor for the development of specialty polymers and advanced organic materials.
• Ligand and Catalyst Development: Employed in the creation of novel ligands for transition metal catalysis, leveraging the iodine atom for further functionalization.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological systems and mechanisms.
• Custom Synthesis and R&D: A fundamental reagent for contract research organizations (CROs) and academic laboratories engaged in novel synthetic route development.

Basic Information

Product Name	2-Iodo-5-Methylbenzoic Acid
CAS No.	52548-14-8
Molecular Formula	C8H7IO2
Molecular Weight	262.05 g/mol
Synonyms	5-Methyl-2-iodobenzoic Acid; 2-Iodo-5-methylbenzoic acid; 2-Iodo-p-toluic Acid; 2-Iodo-5-methyl-benzoic acid; Benzoic acid, 2-iodo-5-methyl-; 5-Methyl-2-iodobenzoic acid; 2-Iodo-5-methylbenzoic acid (CAS 52548-14-8)
EINECS	Contact for details

Quality Control

Our 2-Iodo-5-Methylbenzoic Acid is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques, including HPLC, GC, and NMR, to verify identity and quantify impurities. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment. Our quality system supports compliance with cGMP and ISO standards for research and commercial-scale applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.