Description

(2S,3R,4S,5R)-2-Acetamido-3,5-Dihydroxy-1-Oxo-4,6-Disulfooxy-Hexane CAS NO 52510-51-7 is a high-purity, sulfated N-acetyl hexosamine derivative, a key intermediate in advanced biochemical synthesis. This compound matters for its role as a critical building block in the development of glycosaminoglycan (GAG) mimetics and other complex carbohydrate-based pharmaceuticals. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors who require precise, high-quality intermediates for drug discovery, glycobiology research, and the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A crucial precursor for the synthesis of heparin-like oligosaccharides and other sulfated glycans with therapeutic potential.
• Glycobiology Research: Used as a standard or substrate in enzymatic studies and for investigating carbohydrate-protein interactions.
• Drug Discovery: Serves as a building block for creating novel anti-coagulant, anti-inflammatory, or anti-viral drug candidates targeting glycosaminoglycan pathways.
• Bioconjugation: Utilized in the development of carbohydrate-based vaccines, diagnostics, and targeted drug delivery systems.
• Enzyme Inhibitor Development: Acts as a scaffold for designing inhibitors of sulfotransferases, glycosidases, or other carbohydrate-processing enzymes.
• Biomaterial Synthesis: Incorporated into hydrogels or surface coatings to mimic the extracellular matrix for tissue engineering applications.

Basic Information

Product Name	(2S,3R,4S,5R)-2-Acetamido-3,5-Dihydroxy-1-Oxo-4,6-Disulfooxy-Hexane
CAS No.	52510-51-7
Molecular Formula	C8H13NO13S2
Molecular Weight	395.31 g/mol
Synonyms	N-Acetyl-D-glucosamine-4,6-disulfate; D-Glucosamine, N-acetyl-, 4,6-bis(hydrogen sulfate); 2-Acetamido-2-deoxy-D-glucopyranose 4,6-disulfate; 4,6-Di-O-sulfo-N-acetyl-D-glucosamine; GlcNAc-4,6-disulfate; N-Acetylglucosamine 4,6-disulfate; AGlcNAc-4,6-S; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our (2S,3R,4S,5R)-2-Acetamido-3,5-Dihydroxy-1-Oxo-4,6-Disulfooxy-Hexane is produced under stringent quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (NMR, MS), to ensure it meets exacting standards for research and development use. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive). Allow the sealed container to reach ambient temperature before opening to prevent condensation and moisture ingress.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Assay	≥ 90.0% (on dried basis)
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.