Description

3-(4-Methoxyphenyl)Cyclobutanone is a versatile organic building block featuring a cyclobutanone ring substituted with a 4-methoxyphenyl group. This compound is valued for its unique structural motif, which serves as a key intermediate in the synthesis of complex molecules, particularly in pharmaceutical and advanced material research. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those requiring constrained, four-membered ring systems.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides where the cyclobutanone core imparts specific biological activity.
• Material Science Research: Serves as a monomer or building block for developing polymers and advanced organic materials with tailored thermal or optical properties.
• Organic Synthesis Building Block: Employed in academic and industrial laboratories for ring-expansion reactions, [2+2] cycloadditions, and the preparation of other functionalized cyclobutane derivatives.
• Ligand and Catalyst Development: Utilized in the preparation of chiral ligands or organocatalysts for asymmetric synthesis applications.
• Fragrance and Flavor Chemistry: Acts as an intermediate for synthesizing specific aroma chemicals with complex, musk-like, or woody notes.

Basic Information

Product Name	3-(4-Methoxyphenyl)Cyclobutanone
CAS No.	52498-02-9
Molecular Formula	C11H12O2
Molecular Weight	176.21 g/mol
Synonyms	3-(4-Methoxyphenyl)cyclobutan-1-one; 1-(4-Methoxyphenyl)cyclobutan-3-one; 4-Methoxyphenyl cyclobutanone; p-Methoxyphenylcyclobutanone; Cyclobutanone, 3-(4-methoxyphenyl)-; 52498-02-9
EINECS	Contact for details

Quality Control

Our 3-(4-Methoxyphenyl)Cyclobutanone is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of research and process chemistry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for every shipment upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.