Description

Methyl A-D-Ribofuranoside CAS NO 52485-92-4 is a high-purity, protected ribose derivative that serves as a critical chiral building block and synthetic intermediate in advanced organic chemistry. Its value lies in providing a chemically defined scaffold for the synthesis of nucleoside analogs, antiviral agents, and other biologically active compounds. This product is essential for research and development laboratories, pharmaceutical manufacturers, and fine chemical producers focused on carbohydrate chemistry and medicinal chemistry applications.

Application

• Pharmaceutical Intermediate: Key starting material for the synthesis of nucleoside-based antiviral and anticancer drugs.
• Carbohydrate Chemistry Research: A fundamental chiral synthon for constructing complex oligosaccharides and glycoconjugates.
• Bioconjugation & Probe Development: Used in the preparation of labeled nucleotides and molecular probes for diagnostic applications.
• Fine Chemical Synthesis: Serves as a precursor for specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Academic & Industrial R&D: Employed in method development and exploratory synthesis within organic and medicinal chemistry.

Basic Information

Product Name	Methyl A-D-Ribofuranoside
CAS No.	52485-92-4
Molecular Formula	C6H12O5
Molecular Weight	164.16 g/mol
Synonyms	Methyl α-D-Ribofuranoside; α-D-Ribofuranoside, Methyl; Methyl α-D-Riboside; 1-O-Methyl-α-D-ribofuranose; α-Methyl D-ribofuranoside; Methyl-α-D-ribofuranose; α-D-Ribofuranose, methyl glycoside; NSC 403697
EINECS	Contact for details

Quality Control

Our Methyl A-D-Ribofuranoside is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and purity, chiral analysis to confirm stereochemical integrity, and residual solvent screening. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider using a desiccator or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation [α]20/D	-70° to -75° (c=1 in H2O)
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.