Description

1-Benzyloxy-2-Bromo-4-T-Butylbenzene is a high-purity, synthetically valuable brominated aromatic ether intermediate. This compound is critical for facilitating advanced organic synthesis, particularly in constructing complex molecular architectures where selective functionalization is required. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for use as a key building block in active pharmaceutical ingredient (API) synthesis and specialty chemical manufacturing.

Application

• Pharmaceutical Intermediate: A crucial building block in the multi-step synthesis of novel drug candidates and active pharmaceutical ingredients (APIs), enabling the introduction of the benzyloxy and bromo functional groups.
• Agrochemical Synthesis: Used in research and development for creating new herbicides, fungicides, and pesticides, leveraging its halogenated aromatic structure.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the development of organic semiconductors, liquid crystals, and polymers where its bulky tert-butyl and benzyloxy groups influence material properties.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Sonogashira) to form biaryl and other complex structures.
• Chemical Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	1-Benzyloxy-2-Bromo-4-T-Butylbenzene
CAS No.	52458-11-4
Molecular Formula	C₁₇H₁₉BrO
Molecular Weight	319.24 g/mol
Synonyms	2-Bromo-4-tert-butyl-1-(phenylmethoxy)benzene; 4-tert-Butyl-2-bromo-1-benzyloxybenzene; 1-Benzyloxy-2-bromo-4-tert-butylbenzene; 2-Bromo-1-(benzyloxy)-4-tert-butylbenzene; Benzene, 2-bromo-4-(1,1-dimethylethyl)-1-(phenylmethoxy)-; 2-Bromo-4-(tert-butyl)phenyl benzyl ether; 1-Bromo-2-benzyloxy-5-tert-butylbenzene (isomer reference)
EINECS	Contact for details

Quality Control

Every batch of 1-Benzyloxy-2-Bromo-4-T-Butylbenzene is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, GC, NMR, and IR spectroscopy to ensure identity, purity, and consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) with detailed batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.