Description

1-Bromo-2,3,5,6-Tetramethyl-4-Nitrobenzene is a high-purity, multi-substituted aromatic compound that serves as a critical synthetic intermediate. Its unique structure, featuring bromine and nitro groups on a tetramethylated benzene ring, makes it a valuable building block for creating complex molecules with tailored properties. This product is essential for research and development chemists in the pharmaceutical and advanced materials sectors who require precise, high-quality intermediates for synthesizing active pharmaceutical ingredients (APIs), liquid crystals, and specialty polymers.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs), particularly where steric hindrance and specific electronic properties are required.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, pesticides, and fungicides, leveraging its halogen and nitro functional groups for further chemical transformations.
• Advanced Material Research: Serves as a building block for organic semiconductors, liquid crystals, and specialty polymers where the tetramethyl and nitro groups influence material properties like solubility and electronic characteristics.
• Dye and Pigment Manufacturing: Acts as an intermediate in the production of specialized dyes and pigments, with the nitro group often being a key chromophore component.
• Organic Synthesis & Chemical Research: A versatile reagent for cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution, enabling the construction of diverse chemical libraries.

Basic Information

Product Name	1-Bromo-2,3,5,6-Tetramethyl-4-Nitrobenzene
CAS No.	52415-10-8
Molecular Formula	C10H12BrNO2
Molecular Weight	258.11 g/mol
Synonyms	2,3,5,6-Tetramethyl-1-bromo-4-nitrobenzene; 4-Nitro-1-bromo-2,3,5,6-tetramethylbenzene; Benzene, 1-bromo-2,3,5,6-tetramethyl-4-nitro-; 1-Bromo-2,3,5,6-tetramethyl-4-nitro-benzene; Pentamethylnitrobenzene bromide derivative
EINECS	Contact for details

Quality Control

Our 1-Bromo-2,3,5,6-Tetramethyl-4-Nitrobenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment ensures the material meets the high standards required for research and commercial synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.