Description

Bis(Di-tert-Butyl-Phenylphosphine)Palladium(0), Pd 19.3% is a highly active, air-stable palladium(0) catalyst widely used in cross-coupling reactions. Its value lies in its exceptional performance in demanding synthetic transformations, offering superior reactivity and selectivity compared to many traditional catalysts. This product is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials industries who require reliable and efficient catalytic solutions for complex molecule synthesis.

Application

• Suzuki-Miyaura Cross-Coupling: A premier catalyst for the coupling of aryl/vinyl boronic acids with aryl/vinyl halides or triflates, crucial for biaryl synthesis in drug discovery.
• Buchwald-Hartwig Amination: Enables the efficient formation of C-N bonds for the synthesis of aryl amines, a key structural motif in numerous active pharmaceutical ingredients (APIs).
• Heck Reaction (Mizoroki-Heck): Catalyzes the coupling of aryl/vinyl halides with alkenes for the construction of substituted olefins.
• Sonogashira Coupling: Facilitates the coupling of terminal alkynes with aryl or vinyl halides to form conjugated enynes and aryl alkynes.
• Advanced Material Synthesis: Used in the preparation of organic semiconductors, OLED materials, and conductive polymers.
• Process Chemistry & Scale-Up: Valued for its robustness and consistent performance in pilot plant and manufacturing-scale reactions.

Basic Information

Product Name	Bis(Di-tert-Butyl-Phenylphosphine)Palladium(0), Pd 19.3%
CAS No.	52359-17-8
Molecular Formula	C28H44P2Pd
Molecular Weight	553.00 g/mol
Synonyms	Bis(di-tert-butylphenylphosphine)palladium(0); Pd(dtbpf)2; Palladium(0) bis(di-tert-butylphenylphosphine); Di-tert-butylphenylphosphine palladium(0) dimer (monomer form); Pd(P(t-Bu)2Ph)2; 1,1'-Bis(di-tert-butylphosphino)ferrocene palladium(0) (common misnomer for related complex); Palladium catalyst 52359-17-8; Air-stable Pd(0) catalyst.
EINECS	Contact for details

Quality Control

Our Bis(Di-tert-Butyl-Phenylphosphine)Palladium(0) is manufactured under strict quality protocols to ensure batch-to-batch consistency and high catalytic activity. Each lot is characterized by advanced analytical techniques, including NMR and elemental analysis, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing palladium content, ligand ratio, and purity is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C to maintain long-term stability and prevent oxidation. The material is easily oxidized (store under inert atmosphere) and light-sensitive (store away from light). Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Orange to brown crystalline powder or solid
Identification (IR)	Conforms to structure
Palladium (Pd) Content	19.0% - 19.5%
Purity (HPLC)	≥ 97.0%
Solubility	Soluble in common organic solvents (Toluene, THF, DCM)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.