Description

o-Methylisourea Hemisulfate is a versatile chemical intermediate primarily used in the synthesis of heterocyclic compounds and functionalized guanidines. Its value lies in its role as a protected guanidine precursor, enabling controlled reactions in complex organic synthesis. This product is essential for research and production in the pharmaceutical, agrochemical, and specialty chemical industries, where it serves as a key building block for active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of guanidine-containing drug candidates, including kinase inhibitors and antiviral agents.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators that require guanidine or substituted guanidine moieties.
• Fine Chemical Production: Intermediate for creating dyes, pigments, and other specialty chemicals with specific functional groups.
• Bioconjugation & Protein Modification: Acts as a reagent for modifying peptides and proteins, introducing guanidine groups to alter bioactivity or stability.
• Polymer Chemistry: Monomer or cross-linking agent in the development of specialty polymers with enhanced thermal or mechanical properties.
• Research & Development: Valuable reagent in academic and industrial R&D for exploring new synthetic pathways and novel compound libraries.

Basic Information

Product Name	o-Methylisourea Hemisulfate
CAS No.	52328-05-9
Molecular Formula	C2H6N2O · ½ H2SO4
Molecular Weight	123.12 g/mol (for free base: 74.08 g/mol)
Synonyms	O-Methylisourea Hydrogen Sulfate; Methylisourea Hemisulfate; 2-Methyl-2-iminourea Hemisulfate; Isourea, O-methyl-, sulfate (1:?); Guanidine, O-methyl-, sulfate; Methylguanidine Sulfate (ambiguous); (Methoxyamino)methaniminium Sulfate
EINECS	Contact for details

Quality Control

Our o-Methylisourea Hemisulfate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with key parameters including assay, impurity profile, and moisture content. Our quality commitment supports applications requiring high-purity intermediates for GMP or research-grade synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). Keep the container tightly sealed to minimize exposure to atmospheric humidity. Store away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.