Description

4-Chloro-2-Nitrobenzyl Bromide is a versatile halogenated nitroaromatic building block of significant importance in advanced organic synthesis. Its molecular structure, featuring both a reactive benzyl bromide group and an electron-withdrawing nitro substituent, makes it a critical precursor for constructing complex molecules. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a halogenated benzyl moiety.
• Agrochemical Synthesis: Used in the research and production of herbicides, fungicides, and insecticides, where the nitro and chloro groups contribute to biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in catalytic processes and metal-organic frameworks (MOFs).
• Dye and Pigment Manufacturing: Intermediate in the production of complex organic dyes and pigments, leveraging its nitro-aromatic core.
• Polymer Modification: Employed to introduce functional groups into polymer chains, altering material properties for advanced applications.
• Cross-Coupling Reactions: A valuable substrate in Suzuki, Heck, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Chemical Research: Essential reagent in academic and industrial R&D for exploring new synthetic pathways and novel compound libraries.

Basic Information

Product Name	4-Chloro-2-Nitrobenzyl Bromide
CAS No.	52311-59-8
Molecular Formula	C7H5BrClNO2
Molecular Weight	250.48 g/mol
Synonyms	1-(Bromomethyl)-4-chloro-2-nitrobenzene; (4-Chloro-2-nitrophenyl)methyl bromide; 2-Nitro-4-chlorobenzyl bromide; α-Bromo-4-chloro-2-nitrotoluene; 4-Chloro-2-nitrobenzyl bromide; 4-Chloro-2-nitro-α-bromotoluene; Benzene, 1-(bromomethyl)-4-chloro-2-nitro-; 4-Chloro-2-nitrobenzylbromide
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-Nitrobenzyl Bromide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	68°C - 72°C
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.