Description

2,2-Diethoxyoxolane is a versatile heterocyclic compound and a protected form of succinaldehyde, widely used as a key synthetic intermediate. Its value lies in its ability to act as a masked 1,4-dicarbonyl synthon, enabling the efficient construction of complex molecular frameworks under controlled conditions. This chemical is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries, particularly for the synthesis of pyrroles, macrocycles, and other specialty heterocycles.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds containing pyrrole or tetrahydrofuran rings.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where specific heterocyclic structures are required for bioactivity.
• Fine Chemical Production: Serves as a precursor for dyes, pigments, and complex organic molecules in specialty chemical manufacturing.
• Polymer Chemistry: Employed as a monomer or cross-linking agent in the development of specialty polymers with tailored properties.
• Academic & R&D: A valuable reagent in organic synthesis laboratories for methodological development and the exploration of new chemical entities.
• Flavor & Fragrance Industry: Potential intermediate in the synthesis of certain aroma chemicals and flavoring agents.

Basic Information

Product Name	2,2-Diethoxyoxolane
CAS No.	52263-97-5
Molecular Formula	C8H16O3
Molecular Weight	160.21 g/mol
Synonyms	2,2-Diethoxy-tetrahydrofuran; Succinaldehyde Diethyl Acetal; 1,1-Diethoxy-2,5-dihydrofuran; Tetrahydrofuran-2,2-diyl Diethyl Ether; 2,5-Dihydrofuran-2,2-diyl Diethyl Ether; 2,2-Diethoxy-2,5-dihydrofuran; Succindialdehyde Diethyl Acetal
EINECS	257-786-1

Quality Control

Our 2,2-Diethoxyoxolane is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) for each lot, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated synthesis pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.415 - 1.425
Density (g/mL, 20°C)	0.98 - 1.02

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.