Description

n-(3-Aminopropyl)Piperazine Trihydrochloride is a high-purity, multi-functional organic building block and pharmaceutical intermediate. This compound is valued for its unique structure, which incorporates both primary amine and secondary amine functionalities in a piperazine backbone, making it a versatile synthon for complex molecule construction. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules, particularly those targeting neurological disorders, cancers, and infectious diseases.
• Ligand Synthesis: Used to create chelating agents and ligands for catalysis and metal ion sequestration in industrial processes.
• Polymer Modification: Serves as a cross-linking agent or curing agent in the production of epoxy resins, polyurethanes, and other specialty polymers.
• Agrochemical Research: Employed in the development of novel herbicides, fungicides, and plant growth regulators.
• Bioconjugation: Utilized in biochemical research for protein labeling, antibody-drug conjugate (ADC) development, and probe synthesis due to its reactive amine groups.
• Corrosion Inhibitor Formulation: Acts as a component in formulations designed to protect metals in harsh industrial environments.

Basic Information

Product Name	n-(3-Aminopropyl)Piperazine Trihydrochloride
CAS No.	52198-67-1
Molecular Formula	C7H19N3 • 3HCl
Molecular Weight	279.63 g/mol (as trihydrochloride salt)
Synonyms	1-(3-Aminopropyl)piperazine trihydrochloride; 3-(Piperazin-1-yl)propan-1-amine trihydrochloride; N-(3-Aminopropyl)piperazine hydrochloride (1:3); APPZ • 3HCl; 1-Piperazinepropanamine, trihydrochloride; 3-(1-Piperazinyl)-1-propanamine trihydrochloride
EINECS	Contact for details

Quality Control

Our n-(3-Aminopropyl)Piperazine Trihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR for identification, and titration for assay confirmation, to ensure it meets stringent specifications for research and industrial use. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure containers are kept sealed to prevent absorption of atmospheric moisture which may affect product quality.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.