Description

cis-3A,4,9,9A-Tetrahydro-2,2-Dimethylnaphtho[2,3-D]-1,3-Dioxol-5-Ol is a specialized chiral intermediate and building block of significant importance in fine chemical synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs). Industries requiring high-purity, stereochemically defined intermediates for research and production will find this chemical essential.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Asymmetric Synthesis: Utilized in stereoselective reactions to introduce specific chirality into target compounds.
• Organic Chemistry Research: Serves as a valuable building block in academic and industrial R&D for novel compound libraries.
• Agrochemical Development: Potential intermediate in the synthesis of advanced, biologically active crop protection agents.
• Material Science: Can be used in the development of specialty polymers or liquid crystals requiring specific stereochemistry.
• Catalyst Ligand Precursor: May be employed in the preparation of chiral ligands for asymmetric catalysis.

Basic Information

Product Name	cis-3A,4,9,9A-Tetrahydro-2,2-Dimethylnaphtho[2,3-D]-1,3-Dioxol-5-Ol
CAS No.	52187-19-6
Molecular Formula	C₁₅H₁₈O₃
Molecular Weight	246.30 g/mol
Synonyms	5-Hydroxy-2,2-dimethyl-3a,4,9,9a-tetrahydro-1H-naphtho[2,3-d][1,3]dioxole; (3aR,4S,9S,9aR)-2,2-Dimethyl-3a,4,9,9a-tetrahydro-1H-naphtho[2,3-d][1,3]dioxol-5-ol; cis-2,2-Dimethyl-3a,4,9,9a-tetrahydro-1H-naphtho[2,3-d][1,3]dioxol-5-ol; Chiral naphthodioxole derivative; Tetrahydro-naphthodioxolol; Dioxolane-naphthol intermediate.
EINECS	Contact for details

Quality Control

Our cis-3A,4,9,9A-Tetrahydro-2,2-Dimethylnaphtho[2,3-D]-1,3-Dioxol-5-Ol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity and chemical identity verification, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.