Description

Ethyl 3-(3-Nitrophenyl)-3-oxopropanoate is a versatile β-keto ester derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its value lies in the reactive oxopropanoate moiety and the nitro-substituted aromatic ring, which provide multiple handles for further functionalization. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for constructing complex molecules like heterocycles and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of various drug candidates and active pharmaceutical ingredients (APIs), especially those containing nitrophenyl or β-keto ester pharmacophores.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and plant growth regulators where the nitro group and ester functionality are integral.
• Organic Synthesis Reagent: Serves as a precursor for Michael additions, Claisen condensations, and cyclization reactions to create complex heterocyclic compounds like pyrazoles and isoxazoles.
• Dye and Pigment Manufacturing: Acts as an intermediate in the synthesis of nitroaromatic-based dyes and organic pigments.
• Material Science Research: Utilized in the development of novel organic materials and ligands for metal-organic frameworks (MOFs) or catalysts.
• Academic & R&D: A valuable compound for methodological research in universities and corporate R&D laboratories exploring new synthetic pathways.

Basic Information

Product Name	Ethyl 3-(3-Nitrophenyl)-3-oxopropanoate
CAS No.	52119-38-7
Molecular Formula	C11H11NO5
Molecular Weight	237.21 g/mol
Synonyms	Ethyl 3-oxo-3-(3-nitrophenyl)propanoate; 3-(3-Nitrophenyl)-3-oxopropanoic Acid Ethyl Ester; Ethyl 3-(3-Nitrophenyl)-3-oxopropionate; Ethyl β-oxo-3-nitrobenzenepropanoate; 3-Nitrobenzoylacetic Acid Ethyl Ester; 1-(3-Nitrophenyl)-1,3-butanedione Ethyl Ester (tautomeric form); Acetic acid, (3-nitrobenzoyl)-, ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 3-(3-Nitrophenyl)-3-oxopropanoate is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.