Description

3',4'-Diethyl-1-(1,2,3,4-Tetrahydronaphthalen-2-Yl)Spiro[Piperidine-4,5'-Oxazolidine] is a complex spirocyclic organic compound with a unique molecular architecture, serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in providing a sophisticated, multifunctional scaffold that enables the development of novel compounds with targeted biological or material properties. This high-purity building block is essential for researchers and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries who are engaged in drug discovery, catalyst development, and the synthesis of high-performance materials.

Application

• Pharmaceutical Intermediate: Key building block for the research and synthesis of new chemical entities (NCEs) and active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and cardiovascular drug discovery.
• Agrochemical Research: Used in the development of novel pesticides, herbicides, and fungicides, leveraging its spirocyclic structure for enhanced bioactivity and environmental stability.
• Catalyst & Ligand Synthesis: Serves as a precursor for creating sophisticated chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science: Intermediate in the production of specialty polymers, liquid crystals, and organic electronic materials requiring complex, rigid molecular frameworks.
• Chemical Biology & Proteomics: Employed as a molecular scaffold or linker in the design of chemical probes, enzyme inhibitors, and bioconjugates for target identification and validation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects requiring high-complexity intermediates.

Basic Information

Product Name	3',4'-Diethyl-1-(1,2,3,4-Tetrahydronaphthalen-2-Yl)Spiro[Piperidine-4,5'-Oxazolidine]
CAS No.	52109-31-6
Molecular Formula	C21H31N2O
Molecular Weight	327.49 g/mol
Synonyms	1-(1,2,3,4-Tetrahydronaphthalen-2-yl)-3',4'-diethylspiro[piperidine-4,5'-oxazolidine]; 3',4'-Diethyl-1-(1,2,3,4-tetrahydronaphthalen-2-yl)spiro[piperidine-4,5'-oxazolidin]-2'-one (related ketone); Spiro[piperidine-4,5'-oxazolidine], 3',4'-diethyl-1-(1,2,3,4-tetrahydro-2-naphthalenyl)-; Tetrahydronaphthalen-2-yl spiro-oxazolidine piperidine derivative; UNII-Contact for details; EINECS Contact for details
EINECS	Contact for details

Quality Control

Our 3',4'-Diethyl-1-(1,2,3,4-Tetrahydronaphthalen-2-Yl)Spiro[Piperidine-4,5'-Oxazolidine] is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical characterization using HPLC, GC, NMR, and mass spectrometry to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We support compliance with cGMP and ISO 9001 standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.