Description

11-(Tetrahydro-2H-pyran-2-yloxy)-1-undecyne is a valuable bifunctional chemical intermediate featuring both a terminal alkyne and a protected hydroxyl group. This unique structure makes it a critical building block for the synthesis of complex molecules, enabling precise control over molecular architecture. It is primarily sought after by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for applications in drug discovery, polymer science, and specialty chemical production.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for constructing carbon chains and introducing functional groups via click chemistry.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, where its alkyne moiety allows for modular compound assembly.
• Polymer & Material Science: Serves as a monomer or cross-linking agent for creating specialty polymers, dendrimers, and functionalized surfaces with tailored properties.
• Liquid Crystal & OLED Materials: Employed in the synthesis of advanced organic electronic materials due to its ability to form rigid, conjugated structures.
• Bioconjugation & Probe Development: The terminal alkyne is ideal for Huisgen cycloaddition (click chemistry) to label biomolecules or create diagnostic probes.
• Organic Synthesis & Catalysis Research: A versatile reagent for academic and industrial R&D in developing new synthetic methodologies and catalytic processes.

Basic Information

Product Name	11-(Tetrahydro-2H-pyran-2-yloxy)-1-undecyne
CAS No.	51953-88-9
Molecular Formula	C₁₆H₂₈O₂
Molecular Weight	252.40 g/mol
Synonyms	1-Undecyne, 11-(tetrahydro-2H-pyran-2-yloxy)-; 11-(THP-Oxy)-1-undecyne; 2-((Undec-10-yn-1-yl)oxy)tetrahydro-2H-pyran; Undec-10-yn-1-yl tetrahydro-2H-pyran-2-yl ether; THP-protected 10-undecyn-1-ol; 10-Undecyn-1-ol, 2-tetrahydropyranyl ether; O-(10-Undecynyl)tetrahydropyranol
EINECS	Contact for details

Quality Control

Our 11-(Tetrahydro-2H-pyran-2-yloxy)-1-undecyne is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We can support development and production needs across various purity grades, from research to GMP standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥95% (Research Grade)
Purity (GC/HPLC)	≥98% (Standard Grade)
Water Content (KF)	<0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.