Description

2,2',4,4',5,5'-Hexachlorobiphenyl-Ul-14C is a uniformly carbon-14 labeled isotopologue of a specific polychlorinated biphenyl (PCB) congener. This radiolabeled compound is an essential tool for tracing, quantifying, and studying the environmental fate, metabolic pathways, and toxicological profile of persistent organic pollutants. It is primarily required by environmental testing laboratories, regulatory agencies, and academic research institutions conducting advanced analytical and biochemical studies.

Application

• Analytical Reference Standard: Used as an internal standard or calibrant in high-precision analytical methods like GC-MS and HPLC for the quantification of PCBs in environmental and biological matrices.
• Environmental Fate Studies: Employed in research to track the degradation, transformation, bioaccumulation, and biomagnification of PCBs in soil, water, and sediment systems.
• Metabolic and Toxicokinetic Research: Essential for investigating the absorption, distribution, metabolism, and excretion (ADME) of this PCB congener in in vitro and in vivo models.
• Method Development and Validation: Serves as a critical component in developing and validating new analytical protocols for PCB detection and analysis to meet regulatory requirements.
• Ecotoxicity Testing: Used in studies assessing the impact and long-term effects of PCBs on specific organisms and ecosystems.
• Quality Assurance/Quality Control (QA/QC): Applied in laboratory proficiency testing and as a spike for recovery studies to ensure accuracy and reliability of analytical data.

Basic Information

Product Name	2,2',4,4',5,5'-Hexachlorobiphenyl-Ul-14C
CAS No.	51908-10-2
Molecular Formula	C12H4Cl6 (14C labeled)
Molecular Weight	~360.88 g/mol (unlabeled)
Synonyms	PCB 153-U-14C; 2,2',4,4',5,5'-HexaCB-U-14C; [U-14C]-PCB 153; BZ# 153 (14C-labeled); 2,2',4,4',5,5'-Hexachloro-1,1'-biphenyl-U-14C; Uniformly Labeled Carbon-14 PCB Congener 153; IUPAC: 1,1'-Biphenyl, 2,2',4,4',5,5'-hexachloro-, uniformly labeled with carbon-14
EINECS	Contact for details

Quality Control

Every batch of our radiolabeled chemicals is produced and analyzed to meet exacting standards for radiochemical purity, chemical purity, and specific activity. Comprehensive quality testing, including HPLC and radio-HPLC analysis, is performed to ensure consistency and reliability for research applications. A detailed Certificate of Analysis (COA) specifying the exact concentration, specific activity, solvent, and purity data is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store the solution at the recommended temperature (typically -20°C or as specified on the COA) in a designated radioactive materials area. Ensure proper laboratory ventilation and adhere to all local and international regulations for handling and disposing of radioactive substances.

Specification

Item	Specification
Appearance	Clear solution
Chemical Purity (HPLC)	≥ 98%
Radiochemical Purity	≥ 97%
Specific Activity	50-60 mCi/mmol (Contact for exact value)
Concentration	0.1 mCi/mL in nonane or toluene (Customizable)
Identification (IR/MS)	Conforms to structure

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.