Description

3-Phenyl-6-Chloro-3,4-Dihydro-2H-1,3-Benzooxazine is a high-purity, synthetically valuable heterocyclic compound that serves as a critical building block in advanced organic synthesis. Its unique fused ring structure containing nitrogen and oxygen makes it a versatile intermediate for developing novel active pharmaceutical ingredients (APIs) and functional materials. This compound is primarily sought by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for creating new molecules with targeted properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) agents and other therapeutic small molecules.
• Agrochemical Research: Used as a core scaffold for developing new pesticides, herbicides, and fungicides with enhanced efficacy and selectivity.
• Material Science: Serves as a monomer or functional additive in the development of advanced polymers, liquid crystals, and organic electronic materials.
• Chemical Synthesis Building Block: Employed in heterocyclic chemistry for constructing complex molecular architectures via ring-opening, substitution, and cyclization reactions.
• Academic & Industrial R&D: Utilized in research laboratories for methodological studies, catalysis development, and exploring new chemical spaces.
• Dye & Pigment Intermediate: Potential use in the synthesis of specialized chromophores and functional dyes due to its conjugated system.

Basic Information

Product Name	3-Phenyl-6-Chloro-3,4-Dihydro-2H-1,3-Benzooxazine
CAS No.	51892-04-7
Molecular Formula	C14H12ClNO
Molecular Weight	245.70 g/mol
Synonyms	6-Chloro-3-phenyl-3,4-dihydro-2H-1,3-benzoxazine; 3-Phenyl-6-chloro-3,4-dihydro-2H-benzo[e][1,3]oxazine; 2H-1,3-Benzoxazine, 6-chloro-3-phenyl-3,4-dihydro-; 51892-04-7; 6-Chloro-3-phenyl-2H-1,3-benzoxazine; 3,4-Dihydro-6-chloro-3-phenyl-2H-1,3-benzoxazine
EINECS	Contact for details

Quality Control

Our 3-Phenyl-6-Chloro-3,4-Dihydro-2H-1,3-Benzooxazine is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) detailing all specifications are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.