Description

4'-Nitrophenyl-α-D-Thio-Mannopyranosid is a specialized thioglycoside derivative, a key synthetic intermediate in carbohydrate chemistry and glycobiology research. This compound is valued for its role as a glycosyl donor or acceptor in the synthesis of complex oligosaccharides and glycoconjugates. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of enzyme inhibitors, diagnostic probes, and novel therapeutic agents targeting carbohydrate-processing enzymes.

Application

• Glycobiology Research: As a critical building block for synthesizing mannose-containing oligosaccharides and glycoconjugates to study carbohydrate-protein interactions.
• Enzyme Inhibition Studies: Used to develop and evaluate inhibitors for glycosidases and glycosyltransferases, enzymes implicated in various metabolic diseases.
• Diagnostic Probe Development: Serves as a substrate or intermediate in creating chromogenic or fluorogenic probes for detecting enzymatic activity in biochemical assays.
• Pharmaceutical Intermediate: Employed in the research and development of potential therapeutic agents, including antiviral and anti-inflammatory drugs that target sugar-binding sites.
• Chemical Biology Tool: Utilized for cell surface engineering and metabolic labeling studies to understand glycan function in cellular processes.
• Standards and Reference Material: Supplied as a high-purity analytical standard for quality control and method validation in research laboratories.

Basic Information

Product Name	4'-Nitrophenyl-α-D-Thio-Mannopyranosid
CAS No.	51885-03-1
Molecular Formula	C12H15NO7S
Molecular Weight	317.31 g/mol
Synonyms	p-Nitrophenyl α-D-thiomannopyranoside; 4-Nitrophenyl α-D-thiomannopyranoside; α-D-Mannopyranoside, 4-nitrophenyl 1-thio-; 1-Thio-α-D-mannopyranoside, 4-nitrophenyl; PNPS-Man; p-Nitrophenyl 1-thio-α-D-mannopyranoside; 4-Nitrophenyl 1-thio-α-D-mannopyranoside; α-D-Thiomannopyranoside, 4-nitrophenyl
EINECS	Contact for details

Quality Control

Our 4'-Nitrophenyl-α-D-Thio-Mannopyranosid is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical characterization, including chromatographic purity assessment and structural confirmation. A Certificate of Analysis (COA) detailing identity, purity, and related substances is provided with every shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.