Description

1-Methanesulfonylpyrrole is a versatile heterocyclic building block and sulfonamide derivative of significant interest in advanced organic synthesis. Its value lies in its role as a key intermediate for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for researchers and manufacturers developing active pharmaceutical ingredients (APIs), specialty chemicals, and functional materials, where the introduction of the methanesulfonyl (mesyl) group is a critical synthetic step.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and development of new pesticides, herbicides, and fungicides, where the pyrrole core imparts specific biological activity.
• Material Science: Serves as a monomer or functionalization agent in the creation of advanced polymers, conductive materials, and organic electronic components.
• Chemical Research: Employed in academic and industrial R&D for method development, catalysis studies, and the exploration of new heterocyclic chemistry.
• Ligand and Catalyst Preparation: Useful for modifying ligands in coordination chemistry and creating novel organocatalysts for asymmetric synthesis.

Basic Information

Product Name	1-Methanesulfonylpyrrole
CAS No.	51832-28-1
Molecular Formula	C5H7NO2S
Molecular Weight	145.18 g/mol
Synonyms	1-(Methylsulfonyl)pyrrole; N-Methanesulfonylpyrrole; Pyrrole, 1-(methylsulfonyl)-; 1-Mesylpyrrole; N-Mesylpyrrole; 1-Pyrrolylmethanesulfonate; Methanesulfonic acid pyrrol-1-yl ester
EINECS	Contact for details

Quality Control

Our 1-Methanesulfonylpyrrole is produced under a strict quality management system to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to confirm identity and purity. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.