Description

Ethyl 1,4-Dioxa-8-Azaspiro[4.5]Decane-8-Carboxylate is a versatile heterocyclic building block and protected amino acid derivative. This compound is valued for its role as a key synthetic intermediate in the preparation of complex pharmaceutical molecules and fine chemicals. It is primarily sought by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing spirocyclic or protected amino acid motifs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific heterocyclic architectures.
• Peptidomimetics & Drug Discovery: Serves as a protected scaffold for constructing peptide analogs and exploring new drug candidates in medicinal chemistry.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals and performance materials.
• Academic & Industrial Research: A valuable reagent for methodological development and exploring new chemical reactions in organic synthesis.

Basic Information

Product Name	Ethyl 1,4-Dioxa-8-Azaspiro[4.5]Decane-8-Carboxylate
CAS No.	51787-77-0
Molecular Formula	C10H17NO4
Molecular Weight	215.25 g/mol
Synonyms	8-Ethoxycarbonyl-1,4-dioxa-8-azaspiro[4.5]decane; Ethyl 1,4-Dioxa-8-Azaspiro[4.5]decane-8-carboxylate; 1,4-Dioxa-8-azaspiro[4.5]decane-8-carboxylic acid ethyl ester; Ethyl 1,4-Dioxa-8-azaspiro[4.5]decane-8-carboxylate; Ethyl 8-Aza-1,4-dioxaspiro[4.5]decane-8-carboxylate; 8-Carbethoxy-1,4-dioxa-8-azaspiro[4.5]decane; N-Carbethoxy-4-ketopiperidine ethylene ketal
EINECS	Contact for details

Quality Control

Our Ethyl 1,4-Dioxa-8-Azaspiro[4.5]Decane-8-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key specifications such as assay and impurity profiles. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.