Description

(2S,3Aα,7Aα)-2,3Bβ-Dimethyl-4-Methylene-5-Oxo-6β,6Aβ-Epoxydecahydro-1H-Cyclopenta[A]Pentalene-2α-Carboxylic Acid is a complex, high-purity diterpenoid derivative with a unique fused-ring structure. This compound is valued for its role as a critical advanced pharmaceutical intermediate and a versatile scaffold in synthetic organic chemistry. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and fine chemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of complex drug candidates, particularly those targeting neurological or metabolic pathways.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and the discovery of new bioactive molecules.
• Process Chemistry Development: Serves as a critical intermediate in the scale-up and optimization of synthetic routes for active pharmaceutical ingredients (APIs).
• Asymmetric Synthesis: Utilized in stereoselective reactions due to its defined chiral centers, enabling the construction of enantiomerically pure compounds.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring high structural complexity.
• Reference Standard: Supplied as a high-purity analytical standard for quality control and regulatory testing in pharmaceutical laboratories.

Basic Information

Item	Details
Product Name	(2S,3Aα,7Aα)-2,3Bβ-Dimethyl-4-Methylene-5-Oxo-6β,6Aβ-Epoxydecahydro-1H-Cyclopenta[A]Pentalene-2α-Carboxylic Acid
CAS No.	51741-93-6
Molecular Formula	C₁₅H₂₀O₄
Molecular Weight	264.32 g/mol
Synonyms	Gibberellin A4 Carboxylic Acid; GA4 Acid; (2S,3aS,4S,7aR)-2,4-Dimethyl-3-methylidene-5-oxo-6,7a-epoxy-1,3a,4,5,6,7-hexahydro-2H-cyclopenta[a]pentalene-2-carboxylic acid; 2,3Bβ-Dimethyl-4-methylene-5-oxo-6β,6Aβ-epoxydecahydro-1H-cyclopenta[a]pentalene-2α-carboxylic acid; Diterpenoid intermediate 51741-93-6
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch is subjected to comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support development and regulatory needs with documentation suitable for cGMP and ICH guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Optical Rotation	Specific range provided on COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.