Description

2-Phenylhistamine Dihydrochloride is a high-purity, pharmacologically active histamine derivative, specifically designed for advanced research and development applications. This compound serves as a critical chemical reference standard and building block in the synthesis of novel therapeutic agents and diagnostic tools. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies focused on neurochemistry, immunology, and receptor studies.

Application

• Pharmaceutical Research & Development: Acts as a key intermediate in the synthesis of novel histamine receptor ligands and potential drug candidates targeting H3 and H4 receptors.
• Biochemical Assay Development: Serves as a reference standard and competitive inhibitor in enzyme-linked immunosorbent assays (ELISA) and other receptor-binding studies.
• Neuroscience & Neuropharmacology: Used in academic and industrial research to study the role of histaminergic systems in the central nervous system.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for investigating G-protein-coupled receptor (GPCR) signaling pathways.
• Quality Control & Analytical Standards: Functions as a certified reference material (CRM) for analytical method validation and impurity profiling in pharmaceutical quality control laboratories.

Basic Information

Item	Details
Product Name	2-Phenylhistamine Dihydrochloride
CAS No.	51721-62-1
Molecular Formula	C11H15N3·2HCl
Molecular Weight	278.18 g/mol
Synonyms	2-(2-Phenylethyl)imidazole Dihydrochloride; 2-(2-Phenylethyl)-1H-imidazole Dihydrochloride; 2-(2-Phenylethyl)glyoxaline Dihydrochloride; α-(2-Imidazolyl)phenethylamine Dihydrochloride; 2-(2-Phenylethyl)-1H-imidazole Hydrochloride (1:2); 2-Phenethylimidazole Dihydrochloride
EINECS	Contact for details

Quality Control

Our 2-Phenylhistamine Dihydrochloride is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and residual solvent analysis. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with the stringent requirements of research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.