Description

(3Ar,5R,6As)-3-Hydroxy-7,7-(Ethylidene Acetal)Bicyclo[3.3.0]Octane CAS NO 51716-64-4 is a high-purity, stereochemically defined bicyclic acetal derivative, serving as a critical chiral building block and advanced pharmaceutical intermediate. Its rigid, functionalized structure is essential for synthesizing complex molecules with precise three-dimensional architecture, directly impacting the efficacy and purity of final active pharmaceutical ingredients. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors engaged in developing novel therapeutics and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of prostaglandins, nucleoside analogues, and other complex bioactive molecules.
• Asymmetric Synthesis: Utilized as a versatile scaffold in stereoselective reactions to construct intricate molecular frameworks.
• Medicinal Chemistry Research: Employed in drug discovery programs for structure-activity relationship (SAR) studies and lead optimization.
• Agrochemical Development: Serves as a precursor for creating novel, stereospecific pesticides and plant growth regulators.
• Fine Chemical Production: Used in the manufacture of specialty chemicals, flavors, and fragrances requiring high enantiomeric purity.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic synthesis and catalysis.

Basic Information

Product Name	(3Ar,5R,6As)-3-Hydroxy-7,7-(Ethylidene Acetal)Bicyclo[3.3.0]Octane
CAS No.	51716-64-4
Molecular Formula	C10H16O3
Molecular Weight	184.23 g/mol
Synonyms	(3aR,5R,6aS)-3-Hydroxy-7,7-(Ethylidene Acetal)Bicyclo[3.3.0]Octane; (3aR,5R,6aS)-3-Hydroxy-7,7-ethylidenedioxybicyclo[3.3.0]octane; 7,7-Ethylidenedioxy-3-hydroxybicyclo[3.3.0]octane; Bicyclo[3.3.0]octane-3-ol, 7,7-ethylidenedioxy-, (3aR,5R,6aS)-; 3-Hydroxy-7,7-(ethylidene acetal)bicyclo[3.3.0]octane; Prostaglandin Intermediate; Chiral Bicyclic Acetal.
EINECS	Contact for details

Quality Control

Our (3Ar,5R,6As)-3-Hydroxy-7,7-(Ethylidene Acetal)Bicyclo[3.3.0]Octane is manufactured under strict quality management systems to ensure batch-to-batch consistency and high enantiomeric purity. Production adheres to cGMP guidelines where applicable, and each lot is supported by a comprehensive Certificate of Analysis (COA). The COA includes critical parameters such as chiral purity (HPLC), chemical identity (IR, NMR), and impurity profile, providing full traceability and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which may affect stability and performance. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.