Description

(4,5,6,7-Tetrahydro-1-Benzothiophen-2-Yl)Methanol is a versatile organic building block featuring a tetrahydrobenzothiophene core with a hydroxymethyl functional group. This compound is valued for its role as a key chiral intermediate in the synthesis of complex pharmaceutical molecules and advanced materials. It is primarily sought by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel heterocyclic compounds.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the development of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and cardiovascular drug candidates.
• Agrochemical Synthesis: Used in the research and production of novel pesticides and herbicides, leveraging its fused heterocyclic structure for biological activity.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands used in asymmetric catalysis, enabling the synthesis of enantiomerically pure compounds.
• Material Science Research: Employed in the synthesis of organic semiconductors, conductive polymers, and other advanced functional materials due to its electron-rich thiophene moiety.
• Chemical Biology Probes: Utilized as a scaffold for developing molecular probes and inhibitors to study enzyme function and biological pathways.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes under cGMP or ISO standards.

Basic Information

Product Name	(4,5,6,7-Tetrahydro-1-Benzothiophen-2-Yl)Methanol
CAS No.	51632-08-7
Molecular Formula	C9H12OS
Molecular Weight	168.26 g/mol
Synonyms	2-(Hydroxymethyl)-4,5,6,7-tetrahydro-1-benzothiophene; 4,5,6,7-Tetrahydro-1-benzothiophene-2-methanol; 2-Hydroxymethyl-4,5,6,7-tetrahydrobenzo[b]thiophene; Tetrahydrobenzothiophene-2-methanol; (4,5,6,7-Tetrahydrobenzo[b]thiophen-2-yl)methanol; 2-Methanol-4,5,6,7-tetrahydrobenzothiophene
EINECS	Contact for details

Quality Control

Our (4,5,6,7-Tetrahydro-1-Benzothiophen-2-Yl)Methanol is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, documenting all critical quality attributes. Our production can adhere to cGMP and ISO 9001 standards for pharmaceutical and industrial applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); containers must be kept tightly sealed to prevent absorption of atmospheric moisture, which may affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Specific Optical Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.