Description

o-(3-Fluoro-Benzyl)-Hydroxylamine Hydrochloride is a high-purity, fluorinated hydroxylamine derivative supplied as a hydrochloride salt. This compound serves as a versatile and critical building block in advanced organic synthesis, particularly for the introduction of the N-O functional group. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex molecules. Its specific structure makes it valuable for creating targeted chemical libraries and developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for creating oxime, nitrone, or other N-O containing pharmacophores.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where the fluorobenzyl moiety can enhance biological activity and stability.
• Chemical Biology & Proteomics: Employed as a reagent for protein modification, bioconjugation, or as a precursor for affinity tags and probes.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of specialized polymers and functional materials.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological development and exploratory synthesis projects.
• Custom Synthesis & Scale-up: Serves as a starting material for contract manufacturing organizations (CMOs) engaged in custom synthesis for clients.

Basic Information

Product Name	o-(3-Fluoro-Benzyl)-Hydroxylamine Hydrochloride
CAS No.	51572-90-8
Molecular Formula	C7H9ClFNO
Molecular Weight	177.60 g/mol
Synonyms	N-(3-Fluorobenzyl)hydroxylamine hydrochloride; (3-Fluorobenzyl)hydroxylamine hydrochloride; O-(3-Fluorobenzyl)hydroxylamine HCl; 1-(3-Fluorophenyl)-N-hydroxymethanamine hydrochloride; 3-Fluorobenzylhydroxylamine hydrochloride; N-Hydroxy-1-(3-fluorophenyl)methanamine hydrochloride; Hydroxylamine, N-[(3-fluorophenyl)methyl]-, hydrochloride
EINECS	Contact for details

Quality Control

Our o-(3-Fluoro-Benzyl)-Hydroxylamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF titration for moisture content, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect product stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.