Description

Thiodigalactoside is a synthetic, non-hydrolyzable disaccharide analog specifically designed as a potent and selective inhibitor of galectin-3. This compound matters because it serves as a critical research tool for studying galectin-3-mediated biological processes, including cell adhesion, apoptosis, and immune response modulation. It is essential for researchers and developers in the pharmaceutical, biotechnology, and life sciences sectors who are investigating cancer, fibrosis, and inflammatory diseases.

Application

• Biochemical Research: A key inhibitor for studying the structure, function, and signaling pathways of galectin-3 in vitro and in vivo.
• Drug Discovery & Development: Used as a reference standard and pharmacological tool in high-throughput screening and lead optimization for galectin-3-targeted therapeutics.
• Cancer Research: Investigated for its potential to inhibit galectin-3-driven tumor progression, metastasis, and angiogenesis.
• Fibrosis Studies: Applied in research models to explore the role of galectin-3 in organ fibrosis (e.g., liver, lung, kidney).
• Immunology & Inflammation: Utilized to dissect the involvement of galectin-3 in immune cell activation and chronic inflammatory conditions.
• Diagnostic Development: Serves as a binding competitor in the development of assays and diagnostic kits for galectin-3 detection.

Basic Information

Product Name	Thiodigalactoside
CAS No.	51555-87-4
Molecular Formula	C12H22O10S
Molecular Weight	358.37 g/mol
Synonyms	TDG; 1,1'-Thiobis(1-deoxy-β-D-galactopyranose); β-D-Galactopyranose, 1,1'-[thiobis(methylene)]bis-; 1,1'-Thiodigalactose; Galectin-3 Inhibitor I; Lactose, 1,1'-thiodi-; 4-O-β-D-Galactopyranosyl-1-thio-β-D-galactopyranose; 1-Thio-β-lactose
EINECS	Contact for details

Quality Control

Our Thiodigalactoside is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture to ensure it meets the high standards required for research applications. A comprehensive Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation or storage under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.