Description

2,4-Difluorophenylhydrazine Hydrochloride is a high-purity, halogenated hydrazine derivative that serves as a critical building block in advanced organic synthesis. Its value lies in providing a reactive hydrazine moiety with a difluorinated aromatic ring, enabling the construction of complex heterocyclic scaffolds with tailored electronic properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to synthesize novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of fluorinated heterocycles, such as pyrazoles and indazoles, for drug discovery programs targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used to create novel fluorinated pesticides and herbicides, where the fluorine atoms enhance biological activity, metabolic stability, and lipophilicity.
• Material Science Research: Building block for developing specialty polymers, liquid crystals, and organic electronic materials that benefit from fluorinated aromatic units.
• Chemical Derivatization Agent: Employed in analytical chemistry for the derivatization of carbonyl compounds (aldehydes, ketones) to form stable hydrazones for detection and analysis.
• Academic & R&D Laboratories: Fundamental reagent for methodological development in organic chemistry, particularly in studies involving nucleophilic aromatic substitution and cyclization reactions.

Basic Information

Product Name	2,4-Difluorophenylhydrazine Hydrochloride
CAS No.	51523-79-6
Molecular Formula	C6H5F2N2•HCl
Molecular Weight	190.58 g/mol
Synonyms	(2,4-Difluorophenyl)hydrazine hydrochloride; 1-(2,4-Difluorophenyl)hydrazine hydrochloride; 2,4-DFPH•HCl; Hydrazine, (2,4-difluorophenyl)-, hydrochloride; 2,4-Difluoro-phenyl-hydrazine HCl
EINECS	Contact for details

Quality Control

Every batch of 2,4-Difluorophenylhydrazine Hydrochloride is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and titration methods, to ensure high chemical purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.