Description

1-(tert-Butoxy)-4-(Chloromethyl)Benzene is a versatile aromatic ether and benzyl chloride derivative, serving as a critical bifunctional building block in advanced organic synthesis. Its molecular structure, featuring both a protected phenolic group and a reactive chloromethyl site, makes it invaluable for constructing complex molecular architectures. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a tert-butoxybenzyl-protected phenol moiety.
• Agrochemical Synthesis: Building block for creating herbicides, fungicides, and insecticides where the chloromethyl group enables further functionalization.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for metal-catalyzed reactions and organocatalysts.
• Polymer Chemistry: Monomer or cross-linking agent for producing specialty polymers with specific thermal or chemical resistance properties.
• Material Science Research: Intermediate in the development of organic electronic materials, liquid crystals, and advanced coatings.
• Custom Chemical Synthesis: Serves as a starting material for contract research organizations (CROs) and CDMOs for client-specific molecule construction.

Basic Information

Product Name	1-(tert-Butoxy)-4-(Chloromethyl)Benzene
CAS No.	51503-07-2
Molecular Formula	C11H15ClO
Molecular Weight	198.69 g/mol
Synonyms	4-(Chloromethyl)phenyl tert-butyl ether; 1-tert-Butoxy-4-(chloromethyl)benzene; p-(tert-Butoxy)benzyl chloride; 4-(tert-Butoxy)benzyl chloride; 1-(1,1-Dimethylethoxy)-4-(chloromethyl)benzene; tert-Butyl 4-(chloromethyl)phenyl ether; (4-(tert-Butoxy)phenyl)methyl chloride
EINECS	Contact for details

Quality Control

Every batch of 1-(tert-Butoxy)-4-(Chloromethyl)Benzene is manufactured under a strict quality management system. Our products undergo rigorous quality testing, including chromatographic purity analysis and identity confirmation, to ensure compliance with industry standards and customer specifications. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to the light-sensitive nature and reactive chloromethyl group, minimize exposure to air and moisture during handling.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.