Description

4,6-o-Isopropylidene-D-Glucal, 97% is a protected carbohydrate derivative, specifically a glucal, that serves as a versatile chiral building block in organic synthesis. Its value lies in its role as a key intermediate for the stereoselective synthesis of complex sugars, nucleosides, and other bioactive molecules. This high-purity grade is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries who require reliable and consistent starting materials for advanced synthetic routes.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the production of novel antiviral agents, antibiotics, and glycosidase inhibitors.
• Nucleoside & Carbohydrate Chemistry: Used in the stereocontrolled synthesis of modified nucleosides, C-glycosides, and complex oligosaccharides.
• Agrochemical Synthesis: Serves as a building block for developing chiral active ingredients with specific biological activity.
• Glycobiology Research: A valuable tool for probing enzyme mechanisms and studying carbohydrate-protein interactions.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Academic & R&D Laboratories: A standard reagent for methodological development in asymmetric synthesis and medicinal chemistry.

Basic Information

Product Name	4,6-o-Isopropylidene-D-Glucal, 97%
CAS No.	51450-36-3
Molecular Formula	C9H14O5
Molecular Weight	202.20 g/mol
Synonyms	1,5-Anhydro-2-deoxy-4,6-O-(1-methylethylidene)-D-arabino-hex-1-enitol; 4,6-O-Isopropylidene-D-glucal; 3,4-Dideoxy-4,6-O-isopropylidene-D-glycero-hex-3-enopyranose; D-Glucal, 4,6-O-isopropylidene-; 1,5-Anhydro-2-deoxy-4,6-O-isopropylidene-D-arabino-hex-1-enitol; 4,6-O-(1-Methylethylidene)-D-glucal
EINECS	Contact for details

Quality Control

Our 4,6-o-Isopropylidene-D-Glucal, 97% is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and optical rotation measurement, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Optical Rotation [α]20/D	-50° to -55° (c=1 in CHCl3)
Melting Point	95 - 100 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.